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KMID : 0377619730240010069
Korean Jungang Medical Journal
1973 Volume.24 No. 1 p.69 ~ p.74
Pharmacological Action of Cayratia Japonica Alkaloid(¥°)
òçË£Óì/Jin, Kap Duck
ì°ãêê©/ÚÓêªùÊ/áäî°üº/Lee, Shin Woong/Park, Won Hark/Song, Jae Hwan
Abstract
Pharmacological effect of alkaloid fraction of cayratia japonica was investigated in rabbit ileum.
Cayratia alkaloid over 10-5g/ml concentration, induced contraction of rabbit ileum. Hexamethonium, atropine and tetracaine did not prevent cayratia alkaloid-induced contraction.
Promethazine inhibited the contractile response to cayratia alkaloid. It is suggested that cayratia alkaloid-induced contraction of rabbit ileum is due to the release of histamine from intestinal tissue.
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